Essay examples --

It is already well known that treating LPS to RAW 264.7 cells increases both the latters length and heighten area, as the former is recognized by the latter as a PAMP (Christie). While the general direction of morphological change was predicted, its degree with respect to the assiduousness of LPS root toughened still remained in question. Thus, the investigation assessed the following two aspects of morphological change compared to their negative control groups Difference in average length and surface area of RAW 264.7 cells.As shown in Figure 3 of this investigation, a positive correlation exists between the concentration of LPS solution treated and the difference in average length of RAW 264.7 cells compared to that of those of the negative control group for instance, the latter increased from 14.385 m to 53.763 m as the former increased from 0.1 gml-1 to degree Celsius gml-1. The latters magnitude of increase decreased with each increase in the former, exhibiting the correlati ons logarithmic behavior compared to the latters increase from 25.215 m to 44.001 m as the former increased from 1 gml-1 to 10 gml-1, the latters increase from 44.001 m to 53.763 m as the former increased from 10 gml-1 to 100 gml-1 was marginal. The overall correlation between the two variables shown is strong, as evidenced by its mellowed correlation coefficient value (R2=0.9846) and the absence of outliers throughout the data.Figure 4 of this investigation also displays a positive correlation between the concentration of LPS solution treated and the difference in average surface area of RAW 264.7 cells compared to that of those of the negative control group for instance, the latter increased from 55.714 m2 to 277.400 m2 as the former ... ...ral weaknesses were considered. For instance, fractures in cytoplasmic processes most likely have originated from physical damage rather than from immunologic interactions repeated attempts to attach coverslips onto the SEM specimen stubs us ing carbon adhesive tabs seems to be the cause.Nevertheless, anterior studies on relevant fields show that some transcription factors involved in TLR4 signaling pathway may regulate LPS-induced apoptosis in macrophages (Ma et al. 41827). Connections could and then be drawn between the concentration of LPS solution treated and RAW 264.7 cell death to some degree. The existence of a threshold value for LPS concentration to induce cell death may also explain the logarithmic correlations seen in differences in average length and surface area of RAW 264.7 cells, suggesting a limit to which the cells can undertake immunologic responses.